GW-1516 (Cardarine, GW501516, GW-501,516, GSK-516) is a SARM that acts as a PPARδ modulator. It activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and has been shown to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome. It most likely does this by stimulating fatty acid oxidation.
It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound such as AICAR.The mechanism by which PPARδ agonists increase HDL seems to be a consequence of increased expression of ABCA1, the cholesterol transporter. GW-1516 has a half-life of 16 hours.
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Marc Antoine Arpin –
25lbs less feel great have to combined with sports and health diet. 2 bottles on 8 week
Simard Michel –
J’ai passer plusieurs commande a date et j’ai essayer plusieurs.. MK677,, GW1516,, SR9009,, RAD140,, LGD4033 et l’Ostarine. GW1516 FAIT Exactement ce qu’il est supposé de faire qui est d’augmenté l’endurance.. Mon cardio est plus long et mon rythme cardiaque plus bas.. Très bon produit légitime..
Ronald Tankersley –
Just got mine in the mail can’t wait to try it.