MK-677 (Ibutamoren, MK-0677, L-163,191) is an orally administered growth hormone secretagogue. A secretagogue is a substance that promotes secretion.By this standard, MK-677 can be compared to peptides such as GHRP-6 or Ipamorelin. The main advantage is that it can be administered orally and does not require injections nor does it have the side effects that GHRP-6 does. MK-677 was developed with the intention of combating conditions such as muscle atrophy, osteoporosis and obesity.
MK-677 was shown to increase IGF-1 levels by between 39-89% in several studies. Here are some IGF-1 benefits:
- Increased Fat Oxidation (fat loss).
- Increased Muscle gains (lean mass).
- Tightening up loose skin.
- Healing old injuries.
- Healing Bones, Tendons and Ligaments
Given the fact that is does not compete with GH levels from exogenously administered HGH, it can be used in high cycles.It is important to note that Growth hormone pulse intensity can be increased through 4 possible mechanisms and MK-677 works through all four.
- It increases GHRH (growth hormone releasing hormone) release.
- It amplifies GHRH signaling.
- It reduces somatostatin release which is desirable because somatostatin turns off GH release.
- It inhibits somatostatin receptor signaling.
MK-677 has been associated with improved sleep, better complexion, increased strength and energy, increased nitrogen retention and a better sense of well-being. Some studies showed that MK-677 boosts immune system response. MK-677 has a half-life of 24 hours.
*Everything in this description is publicly available and is intended for informational purposes only. For more detailed information, please conduct your own research and consult with experts in the field.
Great product at a great price
Marc-André Dubé –
Très bien apprécier le service de prosarms avec leur suivi par courriel a chaque étape de la livrasion et la facilité de paiement. Très satisfait!!!
La commande est arrivée dans les temps.
Le produit répond à mes attentes
Martin Trepanier –
Excellant qualité prix et service rapide
The predator –
Gros boost d’appétit.Permet de manger comme si il n’y avait pas de fond.Les muscles grossissent lentement mais surement.
Odimar Tomazeli –
One side effect of MK-677 is that you will feel like you are not sleeping as much as you have. So for me I started the first week 0.5ml a day and then increase to 1ml a day to get the body used too. then you will not feel the this effect but again at least 6hrs of sleep is required.